Protocols Clinical Studies Journal Articles Adjunct Research Physicians' Pages Studies / Clinical Studies / NIH study (MIRA Minocycline in Rheumatoi... United States MIRA study: NIH sponsored clinical study which showed minocycline safe and effective for treating RA "Benefit became evident after 12 weeks of therapy, and the proportion of patients treated with minocycline showing improvement continued to increase through week 48 of the study. . . We observed significant differences favoring minocycline over placebo in the primary outcome measures." BC Tilley, GS Alarcon, et al, Minocycline in Rheumatoid Arthritis: a 48 Week, Double-Blind, Placebo-Controlled Trial, Ann Int Med, 1995; 122:2, pg 81 -89.        The Road Back Foundation: Educational Use Permitted Home | About RBF | Community | Education | Studies | Donate