Nebraska 2nd Followup:

After 4 years of minocycline, 40% of minocycline patients were in remission without the use of any DMARDs or steroids, while only 6% of placebo patients had achieved a remission. JR O'Dell et al, Treatment of Early Seropositive Rheumatoid arthritis with Minocycline, Arth & Rheum, 1999; 42:8, pgs. 1691-1695